Tapentadol-d5 Hydrochloride

• Catalog No.: T007202
• M. F.: C14H24ClNO
• M. W.: 257.79946
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 3-[(2R,3R)-1-(dimethylamino)-2-methyl(4,4,5,5,5-^2H₅)pentan-3-yl]phenol hydrochloride
• IUPAC Traditional name: 3-[(2R,3R)-1-(dimethylamino)-2-methyl(4,4,5,5,5-^2H₅)pentan-3-yl]phenol hydrochloride
• Synonyms: 3-[(1R,2R)-3-(Dimethylamino)-1-(ethyl-d5)-2-methylpropyl]phenol Hydrochloride

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 188-206°C
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A novel, centrally acting oral analgesic with a dual mode of action that has demonstrated efficacy in preclinical and clinical models of pain relief.

REFERENCES

• Boxenbaum, H., et al.: J. Pharm. Sci., 2, 47 (1999)
• Boase, S., et al.: Br. J. Clin. Pharmacol., 54, 493 (1999)
• Armstrong, S., et al.: Psychosomatics, 44, 515 (1999)
• Bjornsson, T., et al.: Drug Metab. Dispos., 31, 815 ( 2003),