Tandospirone-d8_Molecular_structure_CAS_)

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Tandospirone-d8
Catalog No.	T006432	Name	Toronto Research Chemicals
CAS Number		Website	http://www.trc-canada.com
M. F.	C21H29N5O2	Telephone	+1 (416) 665-9696
M. W.	383.48726	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage		Chembase ID: 178071

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SYNONYMS

IUPAC name

(2R,6S)-4-{4-[4-(pyrimidin-2-yl)piperazin-1-yl](²H₈)butyl}-4-azatricyclo[5.2.1.0²,⁶]decane-3,5-dione

IUPAC Traditional name

(2R,6S)-4-{4-[4-(pyrimidin-2-yl)piperazin-1-yl](²H₈)butyl}-4-azatricyclo[5.2.1.0²,⁶]decane-3,5-dione

Synonyms

(3aα,4β,7β,7aα)-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-(piperazinyl-d8)]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione

(3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-(piperazinyl-d8)]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione

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PROPERTIES

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DETAILS

Description (English)

Labelled Tandospirone (T006430). Tandospirone is a 5HT1A receptor partial agonist. Studies indicate that tandospirone significantly reduces haloperidol-induced bradykinesia in a dose dependent manner. The potency of Tandospirone is equal to that of buspir

REFERENCES

Seymour, P.A., et al.: Prog. Clin. Biol. Res., 361, 453 (1990)
Evans, S.M., et al.: J. Pharmacol. Exp. Ther., 271, 683 (1990)