Sumanirole Maleate

• Catalog No.: S790700
• CAS Number: 179386-43-7
• M. F.: C15H17N3O5
• M. W.: 319.31258

SYNONYMS

• IUPAC name: (10S)-10-(methylamino)-1,3-diazatricyclo[6.3.1.0^4,^1^2]dodeca-4,6,8(12)-trien-2-one; (2Z)-but-2-enedioic acid
• IUPAC Traditional name: (10S)-10-(methylamino)-1,3-diazatricyclo[6.3.1.0^4,^1^2]dodeca-4,6,8(12)-trien-2-one; maleic acid
• Synonyms: (5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (2Z)-2-Butenedioate; (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (2Z)-2-Butenedioate

DATABASE IDS

• CAS Number: 179386-43-7

DETAILS

Description (English)

Sumanirole is a high affinity D2 receptor agonist (EC50 values are between 17 and 75 nM in cell-based assays). Sumanirole displays >200-fold selectivity for the D2 receptor against other dopamine receptor subtypes (Ki values are 9.0, 1940, >2190 and >7140

REFERENCES

• McCall, et al.: J. Pharmacol. Exp. Ther., 314 1248 (2005)
• Stephenson, et al.: J. Pharmacol. Exp. Ther., 314 1257 (2005)