3'-Sulphated Lewis X, Methyl Glycoside

• Catalog No.: S699250
• M. F.: C21H37NO18S
• M. W.: 623.57938

SYNONYMS

• IUPAC name: (2S,3S,5S,6R)-2-{[(2R,3S,4R,5R,6R)-5-acetamido-2-(hydroxymethyl)-6-methoxy-4-{[(2S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-3-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxane-4-sulfonoperoxoic acid
• IUPAC Traditional name: (2S,3S,5S,6R)-2-{[(2R,3S,4R,5R,6R)-5-acetamido-2-(hydroxymethyl)-6-methoxy-4-{[(2S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-3-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxane-4-sulfonoperoxoic acid
• Synonyms: 3'-SO4-Gal1-b-4[FUC1-α-3]GlcNAc-b-O-Me, Methyl O-2-α-3-O-(3-sulfo-b-D-galactopyranosyl)-1-b-4-O-[(α-L-fucopyranosyl)-1-α-3]-2-αcetamido-2-deoxy-b-D-glucopyranoside]

PROPERTIES

• Apperance: Amorphous solid
• Solubility: Water

DETAILS

Description (English)

Recently shown to be a good ligand for E- and L-selectins, two calcium-dependent mammalian lectins associated with early steps in the inflammatory response and lymphocyte extravasation into peripheral lymph nodes which makes them good candidates for anti

REFERENCES

• Yuen, C.T., et al.: J. Biol. Chem., 269, 1595 (1994)
• Lubineau, A., et al.: Tetrahedron Letters, 35, 47, 8795 (1994)