Tamoxifen-13C6

• Catalog No.: T006002
• M. F.: C26H29NO
• M. W.: 377.47048903

SYNONYMS

• IUPAC name: dimethyl(2-{4-[(1E)-2-phenyl-1-[(1,2,3,4,5,6-^1^3C₆)phenyl]but-1-en-1-yl]phenoxy}ethyl)amine
• IUPAC Traditional name: dimethyl(2-{4-[(1E)-2-phenyl-1-[(1,2,3,4,5,6-^1^3C₆)phenyl]but-1-en-1-yl]phenoxy}ethyl)amine
• Synonyms: (Z)-2-[4-[1-(phenyl-13C6)-2-phenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine; Tamoxifen-13C6; ICI 47699-13C6; Z-Tamoxifen-13C6; Novaldex-13C6; Mammaton-13C6; trans-Tamoxifen-13C6

DETAILS

Description (English)

A labelled Tamoxifen; a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isof

REFERENCES

• Sutherland, R., et al.: Nature, 267, 434 (1977)
• Lerner, L., et al.: Cancer Res., 50, 4177 (1977)
• Love, R., et al.: J. Clin. Oncol., 20 2559 (1977)