T-2 Toxin

• Catalog No.: T002980
• CAS Number: 21259-20-1
• M. F.: C24H34O9
• M. W.: 466.52136

SYNONYMS

• IUPAC name: (1'S,2S,2'R,4'S,7'R,9'R,10'R,11'R)-11'-(acetyloxy)-2'-[(acetyloxy)methyl]-10'-hydroxy-1',5'-dimethyl-8'-oxaspiro[oxirane-2,12'-tricyclo[7.2.1.0^2,^7]dodecan]-5'-en-4'-yl 3-methylbutanoate
• IUPAC Traditional name: (1'S,2S,2'R,4'S,7'R,9'R,10'R,11'R)-11'-(acetyloxy)-2'-[(acetyloxy)methyl]-10'-hydroxy-1',5'-dimethyl-8'-oxaspiro[oxirane-2,12'-tricyclo[7.2.1.0^2,^7]dodecan]-5'-en-4'-yl 3-methylbutanoate
• Synonyms: Fusariotoxin T 2; Toxin T 2; Insariotoxin; 12,13-Epoxytrichothec-9-ene-3α,4β,8α,15-tetrol 4,15-Diacetate 8-Isovalerate; NSC 138780; (3α,4β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 4,15-Diacetate 8-(3-Methylbutanoate); 4β,15-Diacetoxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-en-3α-ol; 8α-(3-Methylbutyryloxy)-4β,15-diacetoxyscirp-9-en-3α-ol; Mycotoxin T 2; T 2; T 2 mycotoxin; T-2 Lienomycin

DATABASE IDS

• CAS Number: 21259-20-1

DETAILS

Description (English)

T-2 Toxin is a tricothecene mycotoxin produced by fungi of the genus Fusarium. T-2 Toxin induces DNA damage and cell death on prolonged administration.

REFERENCES

• Kim, C., et al.: Cancer Res., 57, 3115 (1997)
• Bottrel, R., et al.: Antimicrob. Agents Chemother., 1999, 43, 856 (1997)
• Murray, P., et al.: J. Immunol., 178, 2623 (1997)
• Choi, H., et al.: Toxicol. Appl. Pharmacol., 240, 46 (1997)
• Amuzie, C., et al.: To