Succinimidyl-6-(biotinamido) Hexanoate

• Catalog No.: S690250
• CAS Number: 72040-63-2
• M. F.: C20H30N4O6S
• M. W.: 454.5404
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 2,5-dioxopyrrolidin-1-yl 6-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanamido}hexanoate
• IUPAC Traditional name: 2,5-dioxopyrrolidin-1-yl 6-{5-[(3aS,4S,6aR)-2-oxo-hexahydrothieno[3,4-d]imidazolidin-4-yl]pentanamido}hexanoate
• Synonyms: NHS-LC-BIOTIN

DATABASE IDS

• CAS Number: 72040-63-2

PROPERTIES

• Apperance: White Solid
• Melting Point: 150-159°C
• Solubility: DMF
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Storage Warning: Moisture Sensitive

DETAILS

Description (English)

A biotinylation reagent incorporating an aminocaproyl “spacer”. This can reduce the steric hindrance in binding avidin to some biotinylated compounds when used to biotinylate both the antibody and the carrier in the Protein Avidin-Biotin Capture System.

REFERENCES

• Hofmann, K., et al.: Biochemistry, 21, 978 (1982)
• Leary, J.J., et al.: PNAS USA, 80, 4045, (1982)
• Suter, M., et al.: Immunology Letters, 13, 313 (1982)
• Gretch, D.R., et al.: Anal. Biochem., 163, 270 (1982)
• Burgess, T.L., et al.: J. Biol. Chem., 269 (3