STn Epitope

• Catalog No.: S687000
• CAS Number: 114661-01-7
• M. F.: C22H37N3O16
• M. W.: 599.53968
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2R,4S,5R,6R)-2-{[(2R,3R,4R,5R,6S)-6-[(2S)-2-amino-2-carboxyethoxy]-5-acetamido-3,4-dihydroxyoxan-2-yl]methoxy}-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
• IUPAC Traditional name: NeuAc(α->6)GalNAc(α1->O)Ser
• Synonyms: 6-O-α-Sialyl-2-acetamido-2-deoxy-α-D-galactopyranosyl-1-O-L-serine; Serinyl 2-Acetamido-2-deoxy-6-O-(α-2-N-Acetylnuraminyl)-α-D-galactopyranosyl; O-[2-(acetylamino)-6-O-(N-acetyl-α-neuraminosyl)-2-deoxy-α-D-galactopyranosyl]-L-serine

DATABASE IDS

• CAS Number: 114661-01-7

PROPERTIES

• Apperance: White Amorphous Solid
• Melting Point: 188°C
• Solubility: Warm Methanol
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Storage Warning: Moisture Sensitive

DETAILS

Description (English)

Sialosyl-Tn epitope is a cancer associated carbohydrate antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. These antigens appear as clusters of glycopeptide repea

REFERENCES

• Kim, J.M., and Roy, R.: Tetrahedron Lett., 38, 3487 (1997)
• Qiu, D., and Koganty, R.: Tetrahedron Lett., 38, 961 (1997)
• Toyokuni, T., and Singhal, A.K.: Chem. Soc. Rev., 231, (1995)