L-Stepholidine

• Catalog No.: S686610
• CAS Number: 16562-13-3
• M. F.: C19H21NO4
• M. W.: 327.37434

SYNONYMS

• IUPAC name: (12bS)-4,10-dimethoxy-7,8,12b,13-tetrahydro-5H-6-azatetraphene-3,11-diol
• IUPAC Traditional name: (12bS)-4,10-dimethoxy-7,8,12b,13-tetrahydro-5H-6-azatetraphene-3,11-diol
• Synonyms: 3,9-Dimethoxy-13aα-Berbine-2,10-diol; (13aS)-5,8,13,13a-Tetrahydro-3,9-dimethoxy-6H-dibenzo[a,g]quinolizine-2,10-diol; (-)-Stepholidine; S-Stepholidine

DATABASE IDS

• CAS Number: 16562-13-3

DETAILS

Description (English)

A tetrahydroprotoberberine agonist at dopamine D1 and antagonist at D2 receptors. It is used for preventing or treating neural diseases. The neural diseases comprise parkinsonism, schizophrenia and dyskinesia which is produced by L-DOPA or medicine to tre

REFERENCES

• Smith, B., et al.: Pharm. Res., 17, 1278 (2000)
• Shou, M., et al.: Eur. J. Pharm. Sci., 26, 151 (20050, Upton, R., et al.: Clin. Exp. Pharmacol. Physiol., 34, 695 (2000)
• Ohno, S., et al.: Drug Metab. Dispos., 37, 32 (2000)