Stauprimide

• Catalog No.: S684700
• CAS Number: 154589-96-5
• M. F.: C35H28N4O5
• M. W.: 584.62062

SYNONYMS

• IUPAC name: N-[(2S,3R,4R,6R)-3-methoxy-2-methyl-16,18-dioxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^2,^6.0^7,^2^8.0^8,^1^3.0^1^5,^1^9.0^2^0,^2^7.0^2^1,^2^6]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-4-yl]-N-methylbenzamide
• IUPAC Traditional name: stauprimide
• Synonyms: N-[(9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1,3-dioxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl]-N-methylbenzamide; N-Benzoyl-7-oxostaurosporine

DATABASE IDS

• CAS Number: 154589-96-5

PROPERTIES

• Solubility: DMSO (20mg/mL); only slightly soluble in EtOH

DETAILS

Description (English)

Stauprimide is an enhancer stem cell differentiation into endoderm. In vitro differentiation of embryonic stem cells is of great interest to regenerative medicine, and current protocols are labor-intensive and expensive. Small molecules that induce or enh

REFERENCES

• Ji, L., et al.: J. Biol. Chem., 270, 13392 (1995)
• D'Amour, K., et al.: Nat. Biotechnol., 23, 1534 (1995)
• Eastham, A., et al.: Cancer Res., 67, 11254 (1995)
• S. Zhu et al.: Cell Stem Cell 4, 416 (1995)
• K.S. Zaret: Cell Stem Cell 4, 373 (2009)