Spironolactone-d6 (Major)

• Catalog No.: S683002
• M. F.: C24H32O4S
• M. W.: 416.57348
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (1'S,2R,2'R,9'R,10'R,11'S,15'S)-9'-(acetylsulfanyl)-2',15'-dimethyl(4,4,4',4',6',9'-^2H₆)spiro[oxolane-2,14'-tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan]-6'-ene-5,5'-dione
• IUPAC Traditional name: (1'S,2R,2'R,9'R,10'R,11'S,15'S)-9'-(acetylsulfanyl)-2',15'-dimethyl(4,4,4',4',6',9'-^2H₆)spiro[oxolane-2,14'-tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan]-6'-ene-5,5'-dione
• Synonyms: 7α-Acetylthio-3-oxo-17α-pregn-4-ene-21,17-carbolactone-d6; SC-9420-d6; (7α,7α)-7-Acetylthyo-17-hydroxy-3-oxopregn-4-one-21-carboxylic Acid γ-Lactone-d6

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 137-139°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia

REFERENCES

• Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975)