Sotalol-d6 Hydrochloride

• Catalog No.: S677302
• M. F.: C12H21ClN2O3S
• M. W.: 308.82474
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: N-[4-(1-hydroxy-2-{[(1,1,1,3,3,3-^2H₆)propan-2-yl]amino}ethyl)phenyl]methanesulfonamide hydrochloride
• IUPAC Traditional name: N-(4-{1-hydroxy-2-[(1,1,1,3,3,3-^2H₆)propan-2-ylamino]ethyl}phenyl)methanesulfonamide hydrochloride
• Synonyms: Sotalex-d6; MJ 1999-d6; 4'-[1-Hydroxy-2-(isopropylamino-d6)ethyl]methanesulfonanilide Hydrochloride; Betapace-d6; dl-Sotalol-d6 Hydrochloride; DL-MJ 1999-d6; N-[4-[1-Hydroxy-2-[(1-methylethyl-d6)amino]ethyl]phenyl]methanesulfonamide Hydrochloride; Darob-d6; Sotacor-d6

PROPERTIES

• Apperance: Off-White to Pale Yellow Solid
• Melting Point: 196-198°C
• Solubility: DMSO
• Solubility: Methanol
• Solubility: Water
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A labelled potent α-adrenergic receptor antagonist. A class III antiarrythmic. It has been shown to prolong action potential and increases the refractory period.

REFERENCES

• Uloth, et al.: J. Med. Chem., 9, 88 (1966)
• Groh, W.J., et al.: Chirality, 5, 8 (1966)
• Pasnani, J.S., et al.: J. Pharmacol. Exp. Ther., 271, 184 (1966)