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Sorafenib-d3_Molecular_structure_CAS_1130115-44-4)
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Sorafenib-d3

Catalog No. S676852 Name Toronto Research Chemicals
CAS Number 1130115-44-4 Website http://www.trc-canada.com
M. F. C21H16ClF3N4O3 Telephone +1 (416) 665-9696
M. W. 464.8249496 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 177832

SYNONYMS

IUPAC name
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-(2H3)methylpyridine-2-carboxamide
IUPAC Traditional name
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-(2H3)methylpyridine-2-carboxamide
Synonyms
BAY-43-9006-d3
4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-(methyl-d3)-2-pyridinecarboxamide

DATABASE IDS

CAS Number 1130115-44-4

PROPERTIES

Certificate of Analysis Download
Apperance Off-White to Light Pink Solid
Melting Point 202-204°C
Solubility Dichloromethane
Solubility Ethyl Acetate
Solubility Methanol (Sparingly)
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
Labelled Sorafenib, a potent RAF kinase inhibitor. Antineoplastic.

REFERENCES

  • Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003)
  • Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2003)
  • Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2003)
  • Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2003)