Sodium (4-Sulfonatobutyl)methanethiosulfonate

• Catalog No.: S671000
• CAS Number: 385398-78-7
• M. F.: C5H11NaO5S3
• M. W.: 270.32261
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: sodium 4-(methanesulfonylsulfanyl)butane-1-sulfonate
• IUPAC Traditional name: sodium 4-(methanesulfonylsulfanyl)butane-1-sulfonate
• Synonyms: 4-[(Methylsulfonyl)thio]-1-butanesulfonic acid, sodium salt; MTSBS

DATABASE IDS

• CAS Number: 385398-78-7

PROPERTIES

• Apperance: White Solid
• Melting Point: 165-170°C
• Solubility: DMSO
• Solubility: Methanol
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Storage Warning: Moisture Sensitive: Desiccate

DETAILS

Description (English)

Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABAA receptor channel and of lactose permease.

REFERENCES

• Duhten, R.L., et al.: Biochemistry, 32, 3139 (1993)
• Yang, N. et al.: Neuron, 16, 113 (1993)
• Kuner, T. et al.: Neuron, 17, 343 (1993)
• Holmgren, M. et al: Neuropharmacology, 35, 797 (1993)
• Chahine, M. et al.: Biochemical & Biophysical Res. Commun., 233