SN-38-d3 Glucuronide

• Catalog No.: S589982
• M. F.: C28H28N2O11
• M. W.: 568.52872
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6S)-6-{[(19S)-19-ethyl-10-[(2,2,2-^2H₃)ethyl]-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-7-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6S)-6-{[(19S)-19-ethyl-10-[(2,2,2-^2H₃)ethyl]-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-7-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: (4S)-4-Ethyl-11-(ethyl-d3)-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 4-Deoxy-β-D-glucopyranosiduronic Acid; 4-Ethyl-11-(ethyl-d3)-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 4-Deoxy-β-D-glucopyranosiduronic Acid

PROPERTIES

• Apperance: Pale Yellow Solid
• Melting Point: >250°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A labelled metabolite of Irinotecan

REFERENCES

• Fujita, K., et al.: Biol. Pharm. Bull., 31, 2137 (2008)
• Sandanaraj, E., et al.: Pharmacogen. J., 8, 174 (2008)
• Chen, K., et al.: Chem. Biol., 15, 1277 (2008)
• Prijovich, Z., et al.: Mol. Canc. Ther., 8, 940 (2008)