Sitaxsentan-13C4 Sodium

• Catalog No.: S493502
• M. F.: C18H14ClN2NaO6S2
• M. W.: 480.85694935

SYNONYMS

• IUPAC name: sodium 1-[3-({[4-chloro-3-(^1^3C)methyl(3,4,5-^1^3C₃)-1,2-oxazol-5-yl]azanidyl}sulfonyl)thiophen-2-yl]-2-(6-methyl-2H-1,3-benzodioxol-5-yl)ethan-1-one
• IUPAC Traditional name: sodium 1-(3-{[4-chloro-3-(^1^3C)methyl(3,4,5-^1^3C₃)-1,2-oxazol-5-yl]azanidylsulfonyl}thiophen-2-yl)-2-(6-methyl-2H-1,3-benzodioxol-5-yl)ethanone
• Synonyms: Thelin-13C4; TBC 11251-13C4; IPI 1040-13C4; Sitaxentan-13C4 Sodium; N-(4-Chloro-3-methyl-5-isoxazolyl-13C4)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]-3-thiophenesulfonamide Sodium; Sitax-13C4

DETAILS

Description (English)

Labelled Sitaxsentan. Selective endothelin A (ETA) receptor antagonist. Antihypertensive. Used in treatment of chronic heart failure.

REFERENCES

• Wu, C., et al.: J. Med. Chem., 40, 1690 (1997)
• Tilton, R.G., et al.: Pulm. Pharmacol. Ther., 13, 87 (1997)
• Horn, E.M., et al.: Expert. Opin. Invest. Drugs, 13, 1483 (1997)
• Langleben, D., et al.: Chest, 126, 1377 (1997)