Sitagliptin Phosphate

• Catalog No.: S491000
• CAS Number: 654671-78-0
• M. F.: C16H16F6N5O5P
• M. W.: 503.2929202
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (3R)-3-amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one phosphoperoxol hydrogen
• IUPAC Traditional name: phosphoperoxol sitagliptin hydrogen
• Synonyms: 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-phosphate

DATABASE IDS

• CAS Number: 654671-78-0

PROPERTIES

• Apperance: White Solid
• Melting Point: 202-204°C
• Solubility: Methanol
• Solubility: Water
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

REFERENCES

• Kim, D., et al.: J. Med. Chem. 48, 141 (2005)
• Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005)
• Bergman, A., et al: Clin. Ther. 28, 55 (2006)