Sitagliptin Carbamoyl β-D-Glucuronide

• Catalog No.: S490995
• CAS Number: 940002-59-5
• M. F.: C23H23F6N5O9
• M. W.: 627.4472392
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-({[(2R)-4-oxo-4-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-1-(2,4,5-trifluorophenyl)butan-2-yl]carbamoyl}oxy)oxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-({[(2R)-4-oxo-4-[3-(trifluoromethyl)-5H,6H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-1-(2,4,5-trifluorophenyl)butan-2-yl]carbamoyl}oxy)oxane-2-carboxylic acid
• Synonyms: 1-[N-[(1R)-3-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]carbamate] β-D-Glucopyranuronic Acid

DATABASE IDS

• CAS Number: 940002-59-5

PROPERTIES

• Apperance: White Solid
• Melting Point: 167-169°C (dec.)
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A metabolite of Sitagliptin.

REFERENCES

• Zander, M., et al.: Lancet, 359, 824 (2002)
• Kim, D., et al.: J. Med. Chem., 48, 141 (2002)
• Bergman, A., et al.: Clin. Ther., 28, 55 (2002)
• Drucker, D., et al.: Cell Metab., 3, 153 (2002)
• Vincent, S., et al.: Drug Metab. Dispos., 35 (2002)