rac-SitagliptinSee: S491000

• Catalog No.: S490990
• CAS Number: 823817-56-7
• M. F.: C16H15F6N5O
• M. W.: 407.3136192
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 3-amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
• IUPAC Traditional name: sitagliptin
• Synonyms: 7-[3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine

DATABASE IDS

• CAS Number: 823817-56-7

PROPERTIES

• Apperance: Light Brown Syrup
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

A trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.

REFERENCES

• Kim, D., et al.: J. Med. Chem., 48, 141 (2005)
• Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005)
• Bergman, A., et al: Clin. Ther., 28, 55 (2006)