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rac-SitagliptinSee: S491000_Molecular_structure_CAS_823817-56-7)
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rac-SitagliptinSee: S491000

Catalog No. S490990 Name Toronto Research Chemicals
CAS Number 823817-56-7 Website http://www.trc-canada.com
M. F. C16H15F6N5O Telephone +1 (416) 665-9696
M. W. 407.3136192 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 177780

SYNONYMS

IUPAC name
3-amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
IUPAC Traditional name
sitagliptin
Synonyms
7-[3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine

DATABASE IDS

CAS Number 823817-56-7

PROPERTIES

Certificate of Analysis Download
Apperance Light Brown Syrup
Solubility Dichloromethane
Solubility Ethyl Acetate
Solubility Methanol
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
A trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.

REFERENCES

  • Kim, D., et al.: J. Med. Chem., 48, 141 (2005)
  • Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005)
  • Bergman, A., et al: Clin. Ther., 28, 55 (2006)