Sinomenine Hydrochloride

• Catalog No.: S487500
• CAS Number: 6080-33-7
• M. F.: C19H37N5O7
• M. W.: 447.52638
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (2R,4R,5R)-2-{[(1S,4S,6R)-4,6-diamino-3-{[(2S)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol
• IUPAC Traditional name: (2R,4R,5R)-2-{[(1S,4S,6R)-4,6-diamino-3-{[(2S)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol
• Synonyms: Sinomenin Hydrochloride; 7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-9α,13α,14α-morphinan-6-one Hydrochloride; (9α,13α,14α)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one Hydrochloride; Cucoline Hydrochloride; (9α,13α,14α)- 7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one Hydrochloride; NSC 76021

DATABASE IDS

• CAS Number: 6080-33-7

PROPERTIES

• Apperance: White Solid
• Melting Point: >235°C (dec.)
• Solubility: DMSO
• Solubility: Ethanol
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

Sinomenine is an optical isomer of Methoxythebainone. Sinomenine was extracted from root of Sinomenium acutum. Sinomenine has anti-inflammatory and analgesic effect.

REFERENCES

• Kitasato, O., et al.: Arch. Exp. Med., 6, 259 (1925)
• Lodge, D., et al.: Eur. J. Pharmacol., 26, 277 (1925)