Simvastatin, 1-Pyreneacetyl Ester

• Catalog No.: S485030
• CAS Number: 193682-18-7
• M. F.: C43H50O7
• M. W.: 678.8529

SYNONYMS

• IUPAC name: 2-oxo-2-(pyren-1-yl)ethyl (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• IUPAC Traditional name: 2-oxo-2-(pyren-1-yl)ethyl (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• Synonyms: [1S-[1α(βS*,δS*),2α,6β,8β,8aα]]-1-pyreneacetic Acid, Anhydride with 8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid

DATABASE IDS

• CAS Number: 193682-18-7

DETAILS

Description (English)

Simvastatin metabolite fluorescence derivatization.

REFERENCES

• Mauro, V.F., et al.: Clin. Pharmacokin., 243, 195 (1986)
• Gamoh, K., et al.: Anal. Sci., 10, 913 (1986)
• Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986)
• Vickers, S., et al.: Drug Metab. Dispos., 18, 138 (1986)