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Simvastatin Hydroxy Acid Ammonium Salt_Molecular_structure_CAS_139893-43-9)
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Simvastatin Hydroxy Acid Ammonium Salt

Catalog No. S485020 Name Toronto Research Chemicals
CAS Number 139893-43-9 Website http://www.trc-canada.com
M. F. C25H43NO6 Telephone +1 (416) 665-9696
M. W. 453.61202 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Hygroscopic, -20°C Freezer, Under Inert Atmosphere Chembase ID: 177772

SYNONYMS

IUPAC name
ammonium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
IUPAC Traditional name
ammonium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
Synonyms
Simvastatin Ammonium Salt
(βR,δR,1S,2S,6R,8S,8aR)-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid Ammonium Salt
Simvastatin Carboxylic Acid Ammonium Salt
Simvastatin Acid Ammonium Salt

DATABASE IDS

CAS Number 139893-43-9

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 128-131°C
Solubility DMSO
Solubility Ethanol
Solubility Methanol
Solubility Water
MSDS Link Download
Storage Condition Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)
A metabolite of Simvastin (S485000). A competitive inhibitor of HMG-CoA reductase.

REFERENCES

  • Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986)
  • Mol, M.J., et al.: Lancet, 2, 936 (1986)