Simvastatin Hydroxy Acid Methyl Ester

• Catalog No.: S485015
• CAS Number: 145576-26-7
• M. F.: C26H42O6
• M. W.: 450.60808
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: methyl (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• IUPAC Traditional name: methyl (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• Synonyms: (βR,δR,1S,2S,6R,8S,8aR)-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid Methyl Ester

DATABASE IDS

• CAS Number: 145576-26-7

PROPERTIES

• Apperance: Clear Colorless Thick Oil
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

An impurity in Simvastatin (S485000) tablets.

REFERENCES

• Endo, A., et al.: J. Antibiot., 29, 1346 (1976)
• Hoffman, W., et al.: J. Med. Chem., 29, 849 (1976)
• Jemal, M., et al.: J. Pharm. Biomed. Anal., 23, 323 (1976)