Simvastatin Dimer Impurity

• Catalog No.: S485010
• CAS Number: 476305-24-5
• M. F.: C50H76O10
• M. W.: 837.13244
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2R,4R)-2-{2-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}-6-oxooxan-4-yl (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• IUPAC Traditional name: (2R,4R)-2-{2-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}-6-oxooxan-4-yl (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• Synonyms: Simvastatin Impurity D

DATABASE IDS

• CAS Number: 476305-24-5

PROPERTIES

• Apperance: White Solid
• Melting Point: 170-180°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Storage Warning: Hygroscopic

DETAILS

Description (English)

An impurity of Simvastatin (Dimer).

REFERENCES

• Wang, L., et al.: J. Pharm. Biomed. Anal., 21, 1243 (2000)
• Srinivasu, M., et al.: J. Pharm. Biomed. Anal., 29, 715 (2000)
• Vuletic, M., et al.: J. Pharm. Biomed. Anal., 37, 715 (2000)