Securinine

• Catalog No.: S241000
• CAS Number: 5610-40-2
• M. F.: C13H15NO2
• M. W.: 217.2637
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (8R)-14-oxa-7-azatetracyclo[6.6.1.0^1,^1^1.0^2,^7]pentadeca-9,11-dien-13-one
• IUPAC Traditional name: (8R)-14-oxa-7-azatetracyclo[6.6.1.0^1,^1^1.0^2,^7]pentadeca-9,11-dien-13-one
• Synonyms: Securinin; NSC 107413; Securinan-11-one; l-Securinine; (6S,11aR,11bS)-9,10,11,11a-Tetrahydro-8H-6,11b-methanofuro[2,3-c]pyrido[1,2-a]azepin-2(6H)-one; 1,2,3,4,10,10a-Hexahydro-10-hydroxy-6,10-methanopyrido[1,2-a]azepine-9(6H),α-acetic Acid γ-Lactone; (-)-Securinine

DATABASE IDS

• CAS Number: 5610-40-2

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: 140-142°C
• Solubility: Alcohol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Extracted from leaves and roots of Securinega suffruticosa Rehder. The most widely studied of these alkaloids, Securinine, is a specific GABA receptor antagonist and has been found to have significant in vivo CNS activity.

REFERENCES

• Friess, S.L., et al.: Toxicol. Appl. Pharmacol., 3, 347 (1961)