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Securinine

Catalog No. S241000 Name Toronto Research Chemicals
CAS Number 5610-40-2 Website http://www.trc-canada.com
M. F. C13H15NO2 Telephone +1 (416) 665-9696
M. W. 217.2637 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 177729

SYNONYMS

IUPAC name
(8R)-14-oxa-7-azatetracyclo[6.6.1.01,11.02,7]pentadeca-9,11-dien-13-one
IUPAC Traditional name
(8R)-14-oxa-7-azatetracyclo[6.6.1.01,11.02,7]pentadeca-9,11-dien-13-one
Synonyms
Securinin
NSC 107413
Securinan-11-one
l-Securinine
(6S,11aR,11bS)-9,10,11,11a-Tetrahydro-8H-6,11b-methanofuro[2,3-c]pyrido[1,2-a]azepin-2(6H)-one
1,2,3,4,10,10a-Hexahydro-10-hydroxy-6,10-methanopyrido[1,2-a]azepine-9(6H),α-acetic Acid γ-Lactone
(-)-Securinine

DATABASE IDS

CAS Number 5610-40-2

PROPERTIES

Certificate of Analysis Download
Apperance Yellow Solid
Melting Point 140-142°C
Solubility Alcohol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
Extracted from leaves and roots of Securinega suffruticosa Rehder. The most widely studied of these alkaloids, Securinine, is a specific GABA receptor antagonist and has been found to have significant in vivo CNS activity.

REFERENCES

  • Friess, S.L., et al.: Toxicol. Appl. Pharmacol., 3, 347 (1961)