D-erythro-Sphingosine (synthetic)

• Catalog No.: S681000
• CAS Number: 123-78-4
• M. F.: C18H37NO2
• M. W.: 299.49188
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol
• IUPAC Traditional name: sphingosine
• Synonyms: (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol; Erythrosphingosine; 2-Amino-4-octadecene-1,3-diol; trans-4-Sphingenine; (-)-Sphingosine

DATABASE IDS

• CAS Number: 123-78-4

PROPERTIES

• Apperance: White to Pale Yellow Solid
• Melting Point: 68-70°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer
• Storage Warning: Store in freezer

DETAILS

Description (English)

Selective inhibitor of protein kinase C activity and phorbol dibutyrate binding in vitro in human platelets; does not inhibit protein kinase A or myosin light chain kinase; inhibits calmodulin-dependent enzymes; natural isomer of sphingosine.

REFERENCES

• Yoon, C., et al.: Mol. Cancer Res., 7, 361 (2009)
• Giussani, P., et al.: J. Biol. Chem., 284, 5088 (2009)
• Chen-Quay, S., et al.: J. Pharm. Sci., 98, 606 (2009)
• Satoh, Y., et al.: J. Biochem., 145, 31 (2009)