Sildenafil

• Catalog No.: S435001
• CAS Number: 139755-83-2
• M. F.: C22H30N6O4S
• M. W.: 474.5764
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one
• IUPAC Traditional name: sildenafil
• Synonyms: 5-[2-Ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one; 1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine

DATABASE IDS

• CAS Number: 139755-83-2

PROPERTIES

• Apperance: White Solid
• Melting Point: 188-190°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

An orally active selective type 5 cGMP phosphodiesterase inhibitor.

REFERENCES

• Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996)
• Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1996)