SIDAG Dye

• Catalog No.: S422800
• CAS Number: 308127-47-1
• M. F.: C49H69N4NaO18S2
• M. W.: 1089.20793
• Storage: Amber Vial, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: sodium 2-[(1E,3E,5E)-7-[(2E)-3,3-dimethyl-5-{[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]carbamoyl}-1-(4-sulfonatobutyl)-2,3-dihydro-1H-indol-2-ylidene]hepta-1,3,5-trien-1-yl]-3,3-dimethyl-5-{[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]carbamoyl}-1-(4-sulfonatobutyl)-3H-indol-1-ium
• IUPAC Traditional name: sodium 2-[(1E,3E,5E)-7-[(2E)-3,3-dimethyl-5-{[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]carbamoyl}-1-(4-sulfonatobutyl)indol-2-ylidene]hepta-1,3,5-trien-1-yl]-3,3-dimethyl-5-{[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]carbamoyl}-1-(4-sulfonatobutyl)indol-1-ium
• Synonyms: 1,1’-Bis-(4-sulfobutyl)-indotricarbocyanine-5,5’-dicarboxylic Acid Diglucamide Monosodium Salt; 1-Deoxy-1-[[[2-[7-[5-[[(1-deoxy-D-glucitol-1-yl)amino]carbonyl]-1,3-dihydro-3,3-dimethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]-1,3,5-heptatrien-1-yl]-3,3-dimethyl-1-(4-sulfobutyl)-3H-indolium-5-yl]carbonyl]amino]-D-glucitol Monosodium Salt

DATABASE IDS

• CAS Number: 308127-47-1

PROPERTIES

• Apperance: Dark Purple Solid
• Melting Point: 209-211°C
• Solubility: Water
• Storage Condition: Amber Vial, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A carbocyanine-based dye for fluorescence optical imaging. It is a highly hydrophilic derivative based on a carbocyanine chromophore identical to ICG, and showing a low plasma binding of ~10%. It has an estimated blood half-life of ~200 min, is 60 times m

REFERENCES

• Meijer, D., et al.: Eur. J. Clin. Pharmacol., 35, 295 (1988)
• Less, J., et al.: Cancer Res., 52, 6371 (1988)
• Dawson, P., et al.: Eur. J. Radiol., 23, 172 (1988)
• Ebert, B., et al.: J. Biomed. Opt., 6, 134 (1988)
• Houston, J., et al.: Photochem. Photobio