Saracatinib

• Catalog No.: S139350
• CAS Number: 379231-04-6
• M. F.: C27H32ClN5O5
• M. W.: 542.02648
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: N-(5-chloro-2H-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(oxan-4-yloxy)quinazolin-4-amine
• IUPAC Traditional name: N-(5-chloro-2H-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(oxan-4-yloxy)quinazolin-4-amine
• Synonyms: 7-[2-[4-Methylpiperazin-1-yl]ethoxy]-5-[[tetrahydropyran-4-yl]oxy]-4-[[6-chloro-2,3-methylenedioxyphenyl]amino]quinazoline; N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine

DATABASE IDS

• CAS Number: 379231-04-6

PROPERTIES

• Apperance: White Solid
• Melting Point: 84-89°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

An oral, selective dual inhibitor of Src and ABL kinase.

REFERENCES

• Schweppe, R., et al.: J. Clin. Endocrinol., Metab., 94, 2199 (2009)
• Chen, Y., et al.: Clin. Canc. Res., 15, 3396 (2009)
• McDermott, U., et al.: Cancer Res., 70, 1625 (2009)