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Salmeterol Fluticasone Propionate Mixture

Catalog No. S090050 Name Toronto Research Chemicals
CAS Number 136112-01-1 Website http://www.trc-canada.com
M. F. C50H68F3NO9S Telephone +1 (416) 665-9696
M. W. 916.1364296 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Chembase ID: 177682

SYNONYMS

IUPAC name
4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)-2-(hydroxymethyl)phenol (1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro-14-{[(fluoromethyl)sulfanyl]carbonyl}-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-14-yl propanoate
IUPAC Traditional name
salmeterol fluticasone propionate
Synonyms
Adoair Diskus
Advair Diskus
(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic Acid S-(Fluoromethyl) Ester mixture with 4-Hydroxy-α1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol
Seretide
Adoair
Flutide Diskus
Advair
Salmeterol-fluticasone propionate mixt.
Seretide Accuhaler

DATABASE IDS

CAS Number 136112-01-1

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
Salmeterol-fluticasone combination as Adoair, dry powder inhlaler/pressured metered-dose inhaler formulation for bronchial asthma, its benefit or demerits as device for inhalation drug delivery system in pharmacokinetics/pharmacodynamics at lung or periph

REFERENCES

  • Currie, G., et al.: Eur. J. Clin. Pharmacol., 59, 11 (2003)
  • Fitzgerald, M., et al.: Drug Discov. Today, 12, 472 (2003)
  • Daley-Yates, P., et al.: Clin. Ther., 31, 370 (2003)