Salmeterol Fluticasone Propionate Mixture

• Catalog No.: S090050
• CAS Number: 136112-01-1
• M. F.: C50H68F3NO9S
• M. W.: 916.1364296

SYNONYMS

• IUPAC name: 4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)-2-(hydroxymethyl)phenol (1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro-14-{[(fluoromethyl)sulfanyl]carbonyl}-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl propanoate
• IUPAC Traditional name: salmeterol fluticasone propionate
• Synonyms: Adoair Diskus; Advair Diskus; (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic Acid S-(Fluoromethyl) Ester mixture with 4-Hydroxy-α1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol; Seretide; Adoair; Flutide Diskus; Advair; Salmeterol-fluticasone propionate mixt.; Seretide Accuhaler

DATABASE IDS

• CAS Number: 136112-01-1

DETAILS

Description (English)

Salmeterol-fluticasone combination as Adoair, dry powder inhlaler/pressured metered-dose inhaler formulation for bronchial asthma, its benefit or demerits as device for inhalation drug delivery system in pharmacokinetics/pharmacodynamics at lung or periph

REFERENCES

• Currie, G., et al.: Eur. J. Clin. Pharmacol., 59, 11 (2003)
• Fitzgerald, M., et al.: Drug Discov. Today, 12, 472 (2003)
• Daley-Yates, P., et al.: Clin. Ther., 31, 370 (2003)