SAG

• Catalog No.: S083600
• CAS Number: 912545-86-9
• M. F.: C28H28ClN3OS
• M. W.: 490.05942
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 3-chloro-N-{[3-(pyridin-4-yl)phenyl]methyl}-N-[(1s,4s)-4-(methylamino)cyclohexyl]-1-benzothiophene-2-carboxamide
• IUPAC Traditional name: 3-chloro-N-{[3-(pyridin-4-yl)phenyl]methyl}-N-[(1s,4s)-4-(methylamino)cyclohexyl]-1-benzothiophene-2-carboxamide
• Synonyms: 3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]- benzo[b]thiophene-2-carboxamide

DATABASE IDS

• CAS Number: 912545-86-9

PROPERTIES

• Apperance: Orange to Red Oil
• Solubility: Water
• Storage Condition: -20°C Freezer
• Storage Warning: Light Sensitive

DETAILS

Description (English)

A potent agonist of Hedgehog (Hh) signalling by activating the Smoothened (Smo) protein function. Studies identify novel properties of molecules displaying potential interest in the treatment of various cancers and brain diseases, and demonstrate that Smo

REFERENCES

• DeCamp, D., et al.: J. Biol. Chem., 275, 26322 (2000)
• Ahn, S., et al.: Nature, 437, 894 (2000)
• Huangfu, D., et al.: Development, 133, 3 (2000)
• Loulier, K., et al.: J. Neurochem., 98, 530 (2000)