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RWJ-67657_Molecular_structure_CAS_215303-72-3)
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RWJ-67657

Catalog No. R925200 Name Toronto Research Chemicals
CAS Number 215303-72-3 Website http://www.trc-canada.com
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SYNONYMS

IUPAC name
4-[4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl]but-3-yn-1-ol
IUPAC Traditional name
4-[4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-(pyridin-4-yl)imidazol-2-yl]but-3-yn-1-ol
Synonyms
JNJ 3026582
4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol
4-(4-Fluorophenyl)-2-(4-hydroxy-1-butynyl)-1-(3-phenylpropyl)-5-(4-Pyridyl)imidazole
RWJ 67657

DATABASE IDS

CAS Number 215303-72-3

PROPERTIES

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DETAILS

Description (English)
RWJ-67657 is a p38 mitogen-activated protein-kinase (p38MAPK) inhibitor. Studies show that RWJ-67657 might provide a useful tool to intervene in the deranged immune response in sepsis and other inflammatory diseases. RWJ 67657 has been shown to inhibit ch

REFERENCES

  • Fijen, J. et al.: Clin. Exp. Immunol., 124, 16 (2001)
  • Westra, J. et al.: Int. Immunopharmacol., 5, 1259 (2001)
  • Westra, J. et al.: Ann. Rheum. Dis., 63, 1453 (2001)