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(R)-Ruxolitinib_Molecular_structure_CAS_941678-49-5)
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(R)-Ruxolitinib

Catalog No. R702000 Name Toronto Research Chemicals
CAS Number 941678-49-5 Website http://www.trc-canada.com
M. F. C17H18N6 Telephone +1 (416) 665-9696
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SYNONYMS

IUPAC name
(3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)propanenitrile
IUPAC Traditional name
(3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}pyrazol-1-yl)propanenitrile
Synonyms
(βR)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile
INCB 018424

DATABASE IDS

CAS Number 941678-49-5

PROPERTIES

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DETAILS

Description (English)
Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.

REFERENCES

  • Shilling, A.D. et al.: Drug Metab. Disp., 38, 2023 (2010)
  • Mesa, R.A.: IDrugs, 13, 394 (2010)
  • Campas-Moya, C.: Drugs Fut., 35, 457 (2010)