Rupintrivir-d4

• Catalog No.: R701702
• M. F.: C31H39FN4O7
• M. W.: 598.6623632
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: ethyl (2E,4S)-4-[(2R,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-{[5-(^2H₃)methyl(^2H)-1,2-oxazol-3-yl]formamido}-4-oxoheptanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
• IUPAC Traditional name: ethyl (2E,4S)-4-[(2R,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-{[5-(^2H₃)methyl(^2H)-1,2-oxazol-3-yl]formamido}-4-oxoheptanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
• Synonyms: (2E,4S)-4-[[(2R,5S)-2-[(4-Fluorophenyl)methyl]-6-methyl-5-[[(5-methyl-3-isoxazolyl-d4)carbonyl]amino]-1,4-dioxoheptyl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-2-pentenoic Acid; AG 7088-d4

PROPERTIES

• Apperance: White Solid
• Melting Point: >155°c (dec.)
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Labelled Rupintrivir. Rupintrivir (formerly AG7088) is an irreversible inhibitor of the human rhinovirus (HRV) 3C protease that has been demonstrated to have in vitro activity against all HRVs tested, consistent with its interaction with a strictly conser

REFERENCES

• Arruda, E., et al.: J. Clin. Microbiol., 35, 2864 ( 1997), Dragovich, P., et al.: J. Med. Chem., 42, 1213 (1999)
• Kaiser, L., et al.: Antivir. Res., 47, 215 (1999)
• Binford, S., et al.: Antimicrob. Agents Chemother., 49, 619 (1999)
• Schmidtke, M., et al.: