Rupintrivir

• Catalog No.: R701700
• CAS Number: 223537-30-2
• M. F.: C31H39FN4O7
• M. W.: 598.6623632
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: ethyl (2E,4S)-4-[(2R,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-[(5-methyl-1,2-oxazol-3-yl)formamido]-4-oxoheptanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
• IUPAC Traditional name: ethyl (2E,4S)-4-[(2R,5S)-2-[(4-fluorophenyl)methyl]-6-methyl-5-[(5-methyl-1,2-oxazol-3-yl)formamido]-4-oxoheptanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
• Synonyms: (2E,4S)-4-[[(2R,5S)-2-[(4-Fluorophenyl)methyl]-6-methyl-5-[[(5-methyl-3-isoxazolyl)carbonyl]amino]-1,4-dioxoheptyl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-2-pentenoic Acid; AG 7088

DATABASE IDS

• CAS Number: 223537-30-2

PROPERTIES

• Apperance: White Solid
• Melting Point: 170-171°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Rupintrivir (formerly AG7088) is an irreversible inhibitor of the human rhinovirus (HRV) 3C protease that has been demonstrated to have in vitro activity against all HRVs tested, consistent with its interaction with a strictly conserved subset of amino ac

REFERENCES

• Arruda, E., et al.: J. Clin. Microbiol., 35, 2864 ( 1997), Dragovich, P., et al.: J. Med. Chem., 42, 1213 (1999)
• Kaiser, L., et al.: Antivir. Res., 47, 215 (1999)
• Binford, S., et al.: Antimicrob. Agents Chemother., 49, 619 (1999)
• Schmidtke, M., et al.: