Rupatadine Fumarate

• Catalog No.: R701650
• CAS Number: 182349-12-8
• M. F.: C30H30ClN3O4
• M. W.: 532.0299
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (2E)-but-2-enedioic acid; 13-chloro-2-{1-[(5-methylpyridin-3-yl)methyl]piperidin-4-ylidene}-4-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaene
• IUPAC Traditional name: 13-chloro-2-{1-[(5-methylpyridin-3-yl)methyl]piperidin-4-ylidene}-4-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaene; fumaric acid
• Synonyms: 8-Chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridinyl)methyl]-4-piperidinylidene]-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (2E)-2-Butenedioate; Rupafin

DATABASE IDS

• CAS Number: 182349-12-8

PROPERTIES

• Apperance: White Solid
• Melting Point: 196-198°C
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

Rupatadine is a dual antagonist of histamine H1 and platelet-activating factor receptors. Rupatadine is used as an antihistaminic.

REFERENCES

• Merlos, M., et al.: J. Pharmacol. Exp. Ther., 280, 114 (1997)
• Guadano, E.M., et al.: Allergy, 59, 766 (1997)