Rufinamide

• Catalog No.: R701550
• CAS Number: 106308-44-5
• M. F.: C28H29ClN4O3
• M. W.: 505.00786
• Storage: -20°C Freezer, store under inert atmosphere

SYNONYMS

• IUPAC name: (18S)-18-{[bis(^2H₃)methylamino]methyl}-17-oxa-4,14,21-triazahexacyclo[19.6.1.1^7,^1^4.0^2,^6.0^8,^1^3.0^2^2,^2^7]nonacosa-1(28),2(6),7(29),8,10,12,22,24,26-nonaene-3,5-dione hydrochloride
• IUPAC Traditional name: (18S)-18-{[bis(^2H₃)methylamino]methyl}-17-oxa-4,14,21-triazahexacyclo[19.6.1.1^7,^1^4.0^2,^6.0^8,^1^3.0^2^2,^2^7]nonacosa-1(28),2(6),7(29),8,10,12,22,24,26-nonaene-3,5-dione hydrochloride
• Synonyms: E 2080; Inovelon; RUF 331; 1-[(2,6-Difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide; CGP 33101

DATABASE IDS

• CAS Number: 106308-44-5

PROPERTIES

• Apperance: White Solid
• Melting Point: 232-234°C
• Solubility: DMSO
• Solubility: Methanol (Sparingly)
• Storage Condition: -20°C Freezer, store under inert atmosphere

DETAILS

Description (English)

Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.

REFERENCES

• Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995)
• Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1995)
• Palhagen, S., et al.: Epilepsy Res., 43, 115 (1995)