Rubitecan

• Catalog No.: R701500
• CAS Number: 91421-42-0
• M. F.: C20H16O4
• M. W.: 320.33864
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (3S)-8-methoxy-3-methyl-1,2,3,4,7,12-hexahydrotetraphene-1,7,12-trione
• IUPAC Traditional name: (3S)-8-methoxy-3-methyl-3,4-dihydro-2H-tetraphene-1,7,12-trione
• Synonyms: (4S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3’,4’:6,7]indolizinol[1,2-b]quinoline-3,14(4H,-12H)-dione; 9-NC; Orathecin; 9-Nitrocamptothecin

DATABASE IDS

• CAS Number: 91421-42-0

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: >255°C (dec.)
• Solubility: DMSO
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Semisynthetic camptothecin which inhibits DNA topoisomerase I. Prodrug of 9-aminocamptothecin. Antineoplastic.

REFERENCES

• Stehlin, J.S., et al.: Int. J. Oncol., 14, 821 (1999)
• Verschraegen, C.F., et al.: Curr. Opin. Oncol. Endocr. Metab. Invest. Drugs, 1, 184 (1999)