SC-53116 Hydrochloride Hydrate

• Catalog No.: S199890
• CAS Number: 879208-42-1
• M. F.: C16H23Cl2N3O2
• M. W.: 360.27872

SYNONYMS

• IUPAC name: N-[(1S,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl]-4-amino-5-chloro-2-methoxybenzamide hydrochloride
• IUPAC Traditional name: N-[(1S,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl]-4-amino-5-chloro-2-methoxybenzamide hydrochloride
• Synonyms: 4-Amino-5-chloro-N-[[(1S,7aS)-hexahydro-1H-pyrrolizin-1-yl]methyl]-2-methoxybenzamide Hydrochloride Hydrate; (1S-cis)-4-Amino-5-chloro-N-[(hexahydro-1H-pyrrolizin-1-yl)methyl]-2-methoxybenzamide Hydrochloride Hydrate

DATABASE IDS

• CAS Number: 879208-42-1

DETAILS

Description (English)

SC-53116 is a 5-HT4 receptor partial agonist. SC-53116 has been shown to ameliorate scopolamine-induced impairment in learning in rats at a does of 10 μg/rat i.c.v and increase population spike amplitude in the CA1 and CA3 fields of the hippocampus at the

REFERENCES

• Robertson, D., et al.: J. Med. Chem., 29, 2 (1986)
• Hadley, M; Bioorg. Med. Chem. Lett., 9, 1147 (1986)
• Rivkin, A., et al.: Clin. Ther., 1952 (1986)