SC-51322

• Catalog No.: S199880
• CAS Number: 146032-79-3
• M. F.: C22H20ClN3O4S
• M. W.: 457.9299
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 6-chloro-N'-{3-[(furan-2-ylmethyl)sulfanyl]propanoyl}-2-oxa-9-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaene-9-carbohydrazide
• IUPAC Traditional name: 6-chloro-N'-{3-[(furan-2-ylmethyl)sulfanyl]propanoyl}-2-oxa-9-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaene-9-carbohydrazide
• Synonyms: 8-Chloro-2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]-dibenz(Z)[b,f][1,4]oxazepine-10(11H)-carboxylic acid hydrazide; 8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic Acid 2-[3-[(2-Furanylmethyl) thio]-1-oxopropyl]hydrazide

DATABASE IDS

• CAS Number: 146032-79-3

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 112-114°C
• Solubility: DMSO
• Solubility: Methanol (Sparingly)
• Storage Condition: Refrigerator

DETAILS

Description (English)

A selective E-prostanoid receptor subtype 1 (EP1) receptor antagonist which shows antihypertensive effects.

REFERENCES

• Guan, Y. et al.: J. Clin. Invest., 117, 2496 (2007)
• Piazuelo, E. et al.: Prostagland. Other Lipid Mediator, 81, 150 (2007)