RTI-336-d3

• Catalog No.: R701252
• M. F.: C24H26Cl2N2O
• M. W.: 429.38204

SYNONYMS

• IUPAC name: (2S,3S)-3-(4-chlorophenyl)-8-methyl-2-[3-(4-methylphenyl)-1,2-oxazol-5-yl]-8-azabicyclo[3.2.1]octane hydrochloride
• IUPAC Traditional name: (2S,3S)-3-(4-chlorophenyl)-8-methyl-2-[3-(4-methylphenyl)-1,2-oxazol-5-yl]-8-azabicyclo[3.2.1]octane hydrochloride
• Synonyms: (1R,2S,3S,5S)-3-(4-Chlorophenyl)-8-(methyl-d3)-2-[3-(4-methylphenyl)-5-isoxazolyl]-8-azabicyclo[3.2.1]octane Hydrochloride; RTI 4229-336-d3; RTI 336-d3; [1R-(exo,exo)]-3-(4-Chlorophenyl)-8-(methyl-d3)-2-[3-(4-methylphenyl)-5-isoxazolyl]-8-azabicyclo[3.2.1]octane Hydrochloride

DETAILS

Description (English)

Labelled RTI-336. RTI-336 is a a phenyltropane cocaine analog that acts selective dopamine reuptake inhibitor. RTI-336 binds to the dopamine transporter with around 20 times the affinity of cocaine but produces relatively mild stimulant effects. RTI-336 i

REFERENCES

• Carroll, F.I. et al.: AAPS J., 8, E196 (2006)
• Czoty, P.W. et al.: Pharmacol. Biochem. Behav., 96, 274 (2006)
• Carroll, F. et al.: Eur. J. Pharmacol., 553, 149 (2006)