RTI-336

• Catalog No.: R701250
• CAS Number: 204069-50-1
• M. F.: C23H24Cl2N2O
• M. W.: 415.35546

SYNONYMS

• IUPAC name: (1R,2S,3S,5S)-3-(4-chlorophenyl)-8-(^2H₃)methyl-2-(3-phenyl-1,2-oxazol-5-yl)-8-azabicyclo[3.2.1]octane hydrochloride
• IUPAC Traditional name: (1R,2S,3S,5S)-3-(4-chlorophenyl)-8-(^2H₃)methyl-2-(3-phenyl-1,2-oxazol-5-yl)-8-azabicyclo[3.2.1]octane hydrochloride
• Synonyms: RTI 4229-336; [1R-(exo,exo)]-3-(4-Chlorophenyl)-8-methyl-2-[3-(4-methylphenyl)-5-isoxazolyl]-8-azabicyclo[3.2.1]octane Hydrochloride; (1R,2S,3S,5S)-3-(4-Chlorophenyl)-8-methyl-2-[3-(4-methylphenyl)-5-isoxazolyl]-8-azabicyclo[3.2.1]octane Hydrochloride; RTI 336

DATABASE IDS

• CAS Number: 204069-50-1

DETAILS

Description (English)

RTI-336 is a a phenyltropane cocaine analog that acts selective dopamine reuptake inhibitor. RTI-336 binds to the dopamine transporter with around 20 times the affinity of cocaine but produces relatively mild stimulant effects. RTI-336 is a potential cand

REFERENCES

• Carroll, F.I. et al.: AAPS J., 8, E196 (2006)
• Czoty, P.W. et al.: Pharmacol. Biochem. Behav., 96, 274 (2006)
• Carroll, F. et al.: Eur. J. Pharmacol., 553, 149 (2006)