RTI-177

• Catalog No.: R701200
• CAS Number: 170939-95-4
• M. F.: C10H8F2N4O
• M. W.: 238.1935264

SYNONYMS

• IUPAC name: 1-[(2,6-difluorophenyl)(^2H₂)methyl]-1H-1,2,3-triazole-4-carboxamide
• IUPAC Traditional name: 1-[(2,6-difluorophenyl)(^2H₂)methyl]-1,2,3-triazole-4-carboxamide
• Synonyms: RTI 4229-177; RTI 177; [1R-(exo,exo)]-3-(4-Chlorophenyl)-8-methyl-2-(3-phenyl-5-isoxazolyl)-8-azabicyclo[3.2.1]octane Hydrochloride; (1R,2S,3S,5S)-3-(4-Chlorophenyl)-8-methyl-2-(3-phenyl-5-isoxazolyl)-8-azabicyclo[3.2.1]octane Hydrochloride

DATABASE IDS

• CAS Number: 170939-95-4

DETAILS

Description (English)

RTI-177 is a phenyltropane cocaine analog that acts as a dopamine-selective uptake inhibitors. RTI-177 has a lower abuse liability than cocaine but with similar potency. RTI-177 does not bind to anticocaine catalytic antibodies that are used as potential

REFERENCES

• Czoty, P.W. et al.: Pharmacol. Biochem. Behav., 96, 274 (2010)
• Kuhar, M.J. et al.: Synapse, 41, 176 (2010)