RTI-112-d3

• Catalog No.: R701107
• M. F.: C17H23Cl2NO2
• M. W.: 344.27602

SYNONYMS

• IUPAC name: methyl (1R,2S,3S,5S)-3-(4-chloro-3-methylphenyl)-8-(^2H₃)methyl-8-azabicyclo[3.2.1]octane-2-carboxylate hydrochloride
• IUPAC Traditional name: methyl (1R,2S,3S,5S)-3-(4-chloro-3-methylphenyl)-8-(^2H₃)methyl-8-azabicyclo[3.2.1]octane-2-carboxylate hydrochloride
• Synonyms: RTI 4229-112-d3; (1R,2S,3S,5S)-3-(4-Chloro-3-methylphenyl)-8-(methyl-d3)-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester Hydrochloride; [1R-(exo,exo)]-3-(4-Chloro-3-methylphenyl)-8-(methyl-d3)-8-Azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester Hydrochloride

DETAILS

Description (English)

Labelled RTI-112. RTI-112 is a synthetic stimulant and cocaine analog belonging to the phenyltropane group. RTI-112 acts as a non-selective serotonin-norepinephrine-dopamine reuptake inhibitor (SNRDI) with similar selectivty to cocaine.

REFERENCES

• Negus, S.S. et al.: Pharmacol. Biochem. Behav., 91, 333 (2009)
• Kimmel, H. et al.: Pharmacol. Biochem. Behav., 86, 458 (2009)
• Lindsey, K. P. et al.: J. Pharmacol. Exp. Therap., 309, 959 (2009)