Rosuvastatin Lactone-d6

• Catalog No.: R700552
• M. F.: C22H26FN3O5S
• M. W.: 463.5223432
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: N-[4-(4-fluorophenyl)-5-[(E)-2-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]ethenyl]-6-[(1,1,1,3,3,3-^2H₆)propan-2-yl]pyrimidin-2-yl]-N-methylmethanesulfonamide
• IUPAC Traditional name: N-[4-(4-fluorophenyl)-5-[(E)-2-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]ethenyl]-6-[(1,1,1,3,3,3-^2H₆)propan-2-yl]pyrimidin-2-yl]-N-methylmethanesulfonamide
• Synonyms: Rosuvastatin-5S-lactone-d6; N-[4-(4-Fluorophenyl)-6-(1-methylethyl-d6)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 62-70°C
• Solubility: Chloroform
• Solubility: Ethyl Acetate,
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Labelled intermediate in the production of Rosuvastatin (R700500) derivatives.

REFERENCES

• Martin, P., et al.: Clin. Ther., 25, 2215 (2003)
• Sakaeda, T., et al.: Pharm. Res., 23, 506 (2003)