Rosuvastatin-d6 Sodium Salt

• Catalog No.: R700502
• M. F.: C22H27FN3NaO6S
• M. W.: 503.5194532
• Storage: Hygroscopic, Refrigerator, Under Inert Atmosphere

SYNONYMS

• IUPAC name: sodium (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-[(1,1,1,3,3,3-^2H₆)propan-2-yl]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate
• IUPAC Traditional name: sodium (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-[(1,1,1,3,3,3-^2H₆)propan-2-yl]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate
• Synonyms: 7-[4-(4-Fluorophenyl)-6-(1-methylethyl-d6)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt

PROPERTIES

• Apperance: Off-white solid
• Melting Point: >95°C (dec.)
• Solubility: DMSO
• Storage Condition: Hygroscopic, Refrigerator, Under Inert Atmosphere

DETAILS

Description (English)

Labelled Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor.

REFERENCES

• Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997)
• Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (1997)
• Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (1997)