Ritonavir-13C3

• Catalog No.: R535003
• M. F.: C37H48N6O5S2
• M. W.: 723.92218451
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (4,5-^1^3C₂)-1,3-thiazol-5-yl(^1^3C)methyl N-[(2S,3S,5S)-3-hydroxy-5-[(2S)-3-methyl-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}butanamido]-1,6-diphenylhexan-2-yl]carbamate
• IUPAC Traditional name: (4,5-^1^3C₂)-1,3-thiazol-5-yl(^1^3C)methyl N-[(2S,3S,5S)-3-hydroxy-5-[(2S)-2-({[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl}amino)-3-methylbutanamido]-1,6-diphenylhexan-2-yl]carbamate
• Synonyms: (3S,4S,6S,9S)-4-Hydroxy-12-methyl-9-(1-methylethyl)-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoic Acid 5-Thiazolylmethyl-13C3 Ester; ABT 538-13C3; Norvir-13C3; A 84538-13C3

PROPERTIES

• Apperance: White Solid
• Melting Point: 60-62°C
• Solubility: Chloroform
• Solubility: Dichloromethane
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A stable labelled selective HIV protease inhibitor Ritonavir (R535000).

REFERENCES

• Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994)
• Ammaranond, P., et al.: J. Clin. Virol., 26, 153(1994)
• Harrigan, P., et al.: J. Infect. Dis., 191, 339 (1994)
• Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788 (2006)