Rifabutin-d6

• Catalog No.: R505002
• M. F.: C46H62N4O11
• M. W.: 847.00468

SYNONYMS

• IUPAC name: (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21E)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-[2-(^2H₃)methyl(3,3,3-^2H₃)propyl]-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1^4,^7.0^5,^3^1.0^2^6,^3^0]tritriacontane-28,4'-piperidin]-1(31),2,4,9,19,21,25,29-octaen-13-yl acetate
• IUPAC Traditional name: (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21E)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-[2-(^2H₃)methyl(3,3,3-^2H₃)propyl]-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1^4,^7.0^5,^3^1.0^2^6,^3^0]tritriacontane-28,4'-piperidin]-1(31),2,4,9,19,21,25,29-octaen-13-yl acetate
• Synonyms: Antibiotic LM 427-d6; Ansamycin-d6; Rifabutine; Mycobutin-d6; 1',4-Didehydro-1-deoxy-1,4-dihydro-5'-(2-methylpropyl)-1-oxorifamycin XIV-d6; Ansatipine-d6; LM 427-d6

DETAILS

Description (English)

Labelled Rifabutin (R505000). Semisynthetic derivative of Rifamycin S that inhibits nucleic acid synthesis. An antibacterial (tuberculostatic).

REFERENCES

• O’Brien, R.J., et al.: Infect. Dis., 9, 519 (1987)
• Anand, R., et al.: Antimicrob. AG. Chemother., 32 (684 (1987)
• Skinner, M.H., et al.: Antimicrob. Agent Chemother., 33, 1237 (1987)