Ribavirin 2,3,5-Tri-O-acetyl

• Catalog No.: R414515
• M. F.: C14H18N4O8
• M. W.: 370.31472
• Storage: Refrigerator

SYNONYMS

• IUPAC name: [(2R,3R,4R,5R)-3,4-bis(acetyloxy)-5-(3-carbamoyl-1H-1,2,4-triazol-1-yl)oxolan-2-yl]methyl acetate
• IUPAC Traditional name: [(2R,3R,4R,5R)-3,4-bis(acetyloxy)-5-(3-carbamoyl-1,2,4-triazol-1-yl)oxolan-2-yl]methyl acetate
• Synonyms: 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide; 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-1,2,4-triazole-3-carboxamide; Tri-O-acetylribavirin

PROPERTIES

• Solubility: Dichloromethane
• Storage Condition: Refrigerator

DETAILS

Description (English)

Protected Ribavirin (R414475), a purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.

REFERENCES

• Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986)
• Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1986)
• Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1986)
• Reichard, O., et al.: Lancet, 351, 83 (1998)