RS 79948-197

• Catalog No.: R700950
• CAS Number: 186002-54-0
• M. F.: C19H29ClN2O3S
• M. W.: 400.96316

SYNONYMS

• IUPAC name: (4aR,12bS,13aS)-1-(ethanesulfonyl)-10-methoxy-2,3,4,4a,5,7,8,12b,13,13a-decahydro-1H-1,6-diazatetraphene hydrochloride
• IUPAC Traditional name: (4aR,12bS,13aS)-1-(ethanesulfonyl)-10-methoxy-2,3,4,4a,5,7,8,12b,13,13a-decahydro-1,6-diazatetraphene hydrochloride
• Synonyms: (8aR,12aS,13aS)-12-(Ethylsulfonyl)-5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-6H-isoquino[2,1-g][1,6]naphthyridine Hydrochloride

DATABASE IDS

• CAS Number: 186002-54-0

DETAILS

Description (English)

.alpha.2A-Adrenoceptor antagonism increases insulin secretion and synergistically augments insulinotropic effect of glibenclamide.

REFERENCES

• Angel, I., et al.: Eur. J. Pharmacol., 154, 191 (1988)
• Ortiz-Alonso, F., et al.: Metabolism, 40, 1160 (1988)
• Altman, J., et al.: Mol. Pharmacol., 56, 154 (1988)
• Abdel-Zaher, A., et al.: Pharmacol. Res., 44, 397 (1988)
• Bleck, C., et al.: Diabetologia,